学術論文 REPORT

神経科

循環器科

  • ・Mizuno T, Mizuno M, Harada K, Takano H, Shinoda A, Takahashi A, Mamada K, Takamura K, Chen A, Iwanaga K, Ono S, Uechi M.
     Surgical correction for sinus venosus atrial septal defect with partial anomalous pulmonary venous connection in a dog. Journal of Veterinary Cardiology, 28:23-30.(2020)

  • ・Takano H, Kokubu A, Sugimoto K, Sunahara H, Aoki T, Fujii Y.
     Left ventricular structural and functional abnormalities in dogs with hyperadrenocorticism. Journal of Veterinary Cardiology.;17:173-181. (2015)

  • ・Takano H, Isogai T, Aoki T, Wakao Y, Fujii Y.
     Feasibility of Radial and Circumferential Strain Analysis Using 2D Speckle Tracking Echocardiography in Cats. The journal of veterinary medical science. ;77(2):193–201.(2015)

  • ・Ishikawa R, Fujii Y, Takano H, Sunahara H, Aoki T, Wakao Y.
     Left Ventricular Reverse Remodeling After Ductal Closure in Dogs with Hemodynamically Significant Patent Ductus Arteriosus. The internatinal journal of applied research in veterinary medicine. ;11(1):66-69.(2013)

  • ・Aoki T, Fujii Y, Sunahara H, Takano H, Wakao Y.
     Modified loop technique in three dogs with mitral regurgitation. The Journal of veterinary medical science. ;75:107-11.(2013)

  • ・Fujii Y, Nishimoto Y, Sunahara H, Takano H, Aoki T.
     Prevalence of patent foramen ovale with right-to-left shunting in dogs with pulmonic stenosis. Journal of veterinary internal medicine. ;26:183-5.(2012)

  • ・Takano H, Fujii Y, Yugeta N, Takeda S, Wakao Y.
     Assessment of left ventricular regional function in affected and carrier dogs with Duchenne muscular dystrophy using speckle tracking echocardiography. BMC cardiovascular disorders.;11:23.(2011)

  • ・Takano H, Fujii Y, Ishikawa R, Aoki T, Wakao Y.
     Comparison of left ventricular contraction profiles among small, medium, and large dogs by use of two-dimensional speckle-tracking echocardiography. American journal of veterinary research. ;71:421-7.(2010)

  • ・Fujii Y, Aoki T, Takano H, Ishikawa R and Wakao Y.
     Arteriovenous shunts resembling patent ductus arteriosus in dogs: 3 cases. Journal of veterinary cardiology. ;11:147-51.(2009)

外科

  • ・Azuma K, Monnet E:
     A commercially available physical simulator can be used to teach canine laparoscopic cholecystectomy with 2D and 3D visualization. J Am Vet Med Assoc (2026)

  • ・Azuma K, Shropshire S, Ohlendorf A, Monnet E:
     Laparoscopic-assisted fluoroscopic cholangiography is a feasible technique for visualizing the biliary system in canine cadavers. Am J Vet Res (2025)

  • ・Azuma K, Mason G, Monnet E:
     Examination of the thickness of the different components of gallbladder wall in cases with mucocele and/or cholecystitis. Am J Vet Res 85(9):ajvr.24.03.0058 (2024)

  • ・Azuma K, Monnet E:
     Three-dimensional versus two-dimensional laparoscopy for cholecystectomy in a canine cadaveric study. Vet Surg 53(4):695-700 (2024). 

  • ・Azuma K, Ohmi A, Goto-Koshino Y, et al.:
     Outcomes and prognostic factors in canine epitheliotropic and nonepitheliotropic cutaneous T-cell lymphomas. Vet Comp Oncol 20(1):118-126 (2022)

  • ・Uchida M, Ohmi A, Fujiwara R, Fukushima K, Doi A, Azuma K, Tsujimoto H:
     Treatment with rivaroxaban and monitoring of coagulation profiles in two dogs with venous thromboembolism. J Vet Med Sci 82(9):1271-1276 (2020)

  • ・Azuma K, Asakawa M, Fukuda S, Goto-Asakawa M, et al.:
     Hypoglycemia associated with insulin-like growth factor-I producing tonsillar squamous cell carcinoma with disseminated metastasis in a dog. Vet Clin Pathol 48(3):429-434 (2019)

  • ・Azuma K, Kanemoto H, Ohno K, Tsujimoto H, et al.:
     Pneumatosis coli after partial ligation of congenital portosystemic shunt in a dog. J Vet Med Sci 80(10):1549-1552 (2018)

  • ・Sakurai M, Azuma K, Nagai A, Morita T, et al.:
     Neurolymphomatosis in a cat. J Vet Med Sci 78(6):1063-1066 (2016)

  • ・Anis Z, Morita T, Azuma K, Shimada A, et al.:
     Histopathological alterations in immune organs of chickens and ducks after experimental infection with virulent 9a5b Newcastle disease virus. J Comp Pathol 149(1):82-93 (2013)

  • ・Anis Z, Morita T, Azuma K, Shimada A, et al.:
     Comparative study on the pathogenesis of the generated 9a5b Newcastle disease virus mutant isolate between chickens and waterfowl. Vet Pathol 50(4):638-647 (2013)

  • ・Azuma K, Morita T, Koizumi K, Shimada A, et al.:
     Feline gastrointestinal eosinophilic sclerosing fibroplasia in a cat. Jpn J Vet Sci 65(11):879-882 (2012)

  • ・Azuma, K., Asakawa, M, Konno, T., Fukuda, S., Goto Asakawa M.
     Hypoglycemia associated with disseminated metastatic tonsillar squamous cell carcinoma producing insulin-like growth factor-I in a Pomeranian dog. Veterinary Clinical Pathology. . 48; 429-434.(2019)

  • ・Mitsui A、Rosen S, Yaxley P, Lapsley J, Tremolada G, Selmic LE.
     Hypercoagulability based on thromboelastography is common in dogs undergoing adrenalectomy. J Am Vet Med Assoc. 2024 Apr 12;262(6):1-6. doi: 10.2460/javma.23.08.0456. (2024 )

  • ・Gilson SD, Lillian R, Mitsui A,
     “Adrenalectomy”. Current Techniques in Small Animal Surgery 5th Edition. Ed. M Joseph Bojrab. Jackson: Teton New Media, (2014)

  • ・Mitsui A, Mathews KG et al:
     Effects of Fascial Abrasion, Fasciotomy, and Fascial Excision on Cutaneous Wound Healing in Cats. Am J Vet Res ;70(4):532-8(2009)

病理科

内科

  • ・Lopez-Jimenez C, Černá P, Fukushima K, Nakashima K, Nakagawa T, Adam F, Israeliantz N, Denning A, de la Puerta A:
     Ultrasonographic features of feline gastrointestinal eosinophilic sclerosing fibroplasia on initial presentation and during follow-up. Vet Radiol Ultrasound 66(1):e13479 (2025)

  • ・Černá P, Lopez-Jimenez C, Fukushima K, Nakashima K, Nakagawa T, Adam F, Groth A, Denning A, Israeliantz N, Gunn-Moore DA:
     Clinicopathological findings, treatment, and outcome in 60 cats with gastrointestinal eosinophilic sclerosing fibroplasia. J Vet Intern Med 38(2):1005-1012 (2024)

  • ・Sato M, Shropshire SB, Veir JK, Lappin MR:
     Ehrlichia canis, in dogs experimentally infected, treated, and then immune suppressed during the acute or subclinical phases. J Vet Intern Med 34:1214-1221 (2020)

  • ・Graham JA, Sato M, Moor AR, McGrew AK, Ballweber LR, Byas AD, Dowers KL:
     Strongyloides stercoralis disseminated infection in a dog treated with budesonide. J Am Vet Med Assoc 254:974-978 (2019)

  • ・Sato M, Mochizuki H, Goto-Koshino Y, Fujiwara-Igarashi A, Takahashi M, Ohno K, Tsujimoto H:
     Prognostic significance of hypermethylation of death-associated protein kinase (DAPK) gene CpG island in dogs with high-grade B-cell lymphoma. Vet Comp Oncol 16:409-415 (2018)

  • ・Sato M, Veir JK, Legare M, Lappin MR:
     A retrospective study on the safety and efficacy of leflunomide in dogs. J Vet Intern Med 31:1502-1507 (2017)

  • ・Sato M, Yamazaki J, Goto-Koshino Y, Setogushi A, Takahashi M, Baba K, Fujino Y, Ohno K, Tsujimoto H:
     Minimal residual disease in canine lymphoma: an objective marker to assess tumor cell burden in remission. Vet J 215:38-42 (2016)

  • ・Sato M, Mochizuki H, Goto-Koshino Y, Fujiwara-Igarashi A, Takahashi M, Fujino Y, Ohno K, Tsujimoto H:
     Hypermethylation of the death-associated protein kinase CpG island in dogs with canine B-cell lymphoid tumors. Vet Immunol Immunopathol 161:222-231 (2014)

  • ・Sato M, Storb R, Loretz C, Stone D, Mielcarek M, Sale GE, Rezvani AR, Graves SS:
     Inducible costimulatory (ICOS) up-regulation on activated T-cells in chronic graft-versus-host disease after dog leukocyte antigen-nonidentical hematopoietic cell transplantation: a potential therapeutic target. Transplantation 96:34-41 (2013)

  • ・Sato M, Yamazaki J, Goto-Koshino Y, Takahashi M, Fujino Y, Ohno K, Tsujimoto H:
     The prognostic significance of minimal residual disease in the early phases of chemotherapy in dogs with high-grade B-cell lymphoma. Vet J 195:319-324 (2012)

  • ・Sato M, Kanemoto H, Kagawa Y, Kobayashi T, Goto-Koshino Y, Mochizuki H, Takahashi M, Fujino Y, Ohno K, Tsujimoto H:
     Evaluation of prognostic significance of BCL6 gene expression in canine high-grade B-cell lymphoma. Vet J 191:108-114 (2012)

  • ・Sato M, Yamazaki J, Takahashi M, Goto-Koshino Y, Fujino Y, Ohno K, Tsujimoto H:
     Evaluation of cytoreductive efficacy of vincristine, cyclophosphamide, and doxorubicin in dogs with lymphoma by measuring the number of neoplastic lymphoid cells with real-time polymerase chain reaction. J Vet Intern Med 25:285-291 (2011)

  • ・Sato M, Yamazaki J, Takahashi M, Goto-Koshino Y, Fujino Y, Ohno K, Tsujimoto H:
     Increase in minimal residual disease (MRD) in peripheral blood before clinical relapse in dogs with lymphoma that achieved complete remission after chemotherapy. J Vet Intern Med 25:292-296 (2011)

  • ・Sato M, Goto-Koshino Y, Mochizuki H, Fujino Y, Ohno K, Tsujimoto H:
     Perfusion method for harvesting bone marrow cells from dogs. Am J Vet Res 72:1344-1348 (2011)

  • ・Sato M, Goto-Koshino Y, Kanemoto H, Mochizuki H, Fujino Y, Ohno K, Tsujimoto H:
     Characterization of canine BCL6 cDNA and detection systems for its protein expression. Vet Immunol Immunopathol 140:166-169 (2011)

  • ・Fukushima K, Lappin M, Legare M, Veir J:
     A retrospective study of adverse effects of mycophenolate mofetil administration to dogs with immune-mediated disease. J Vet Intern Med 35(5):2215-2221 (2021)

  • ・Kanemoto Y, Fukushima K, Kanemoto H, Ohno K, Tsujimoto H:
     Long-term management of a dog with idiopathic megaesophagus and recurrent aspiration pneumonia by use of an indwelling esophagostomy tube for suction of esophageal content and esophagogastric tube feeding. J Vet Med Sci ;79(1):188-191(2017)

  • ・Fukushima K, Eguchi N, Ohno K, Kanemoto H, Takahashi M, Igarashi H, Ohmi A, Nakashima K, Tsujimoto H:
     Efficacy of leflunomide for treatment of refractory inflammatory colorectal polyps in 15 Miniature Dachshunds. J Vet Med Sci ;78(2):265-269(2016)

  • ・Fukushima K, Fujiwara R, Yamamoto K, Kanemoto H, Ohno K, Tsuboi M, Uchida K, Matsuki N, Nishimura R, Tsujimoto H:
     Characterization of triple-phase computed tomography in dogs with pancreatic insulinoma. J Vet Med Sci ;77(12):1549-1553(2016)

  • ・Fukushima K, Kanemoto H, Ohno K, Takahashi M, Fujiwara R, Nishimura R, Tsujimoto H:
     Computed tomographic morphology and clinical features of extrahepatic portosystemic shunts in 172 dogs in Japan. Vet J ;199(3):376-381(2014)

  • ・Fukushima K, Kanemoto H, Ohno K, Takahashi M, Nakashima K, Fujino Y, Uchida K, Fujiwara R, Nishimura R, Tsujimoto H:
     CT characteristics of primary hepatic mass lesions in dogs. Vet Radiol Ultrasound ;53(3):252-257(2012)

  • ・Fukushima K, Ohno K, Koshino-Goto Y, Uchida K, Nomura K, Takahashi M, Nakashima K, Fujino Y, Tsujimoto H:
     Sensitivity for the detection of a clonally rearranged antigen receptor gene in endoscopically obtained biopsy specimens from canine alimentary lymphoma. J Vet Med Sci ;71(12):1673-1676(2009)

  • ・Fukushima K, Okai Y, Matsuura S, Tsujimoto H, Endo Y:
     Molecular cloning of feline lung resistance-related protein (LRP) cDNA and its expression in a feline lymphoma cell line and adriamycin-resistant subline. J Vet Med Sci ;68(8):885-890(2006)

放射線腫瘍科

  • ・De Mello Souza CH, Shiomitsu K, Hwang B:
     Cytokine production and the effects of oclacitinib in three canine mast cell tumor cell lines. Vet Dermatol ;33(2)(2022)

  • ・Engelien JL, Lejeune AT, Frasca S Jr, Dark MJ, Milner R, Hernandez O, Shiomitsu K:
     RNA in situ hybridization as a molecular diagnostic technique targeting IBA-1 and CD204 in canine histiocytic sarcoma. Vet Comp Oncol (2022)

  • ・Ackerman LH, de Mello Souza CH, Cortés-Hinojosa G, Salute ME, Stephen AA, Anthony E, Shiomitsu K, Milner RJ:
     Identification of the interleukin-8 (CXCL-8) pathway in feline oral squamous cell carcinoma – A pilot study. Can J Vet Res ;86(1):13-19(2022)

  • ・Ehling TJ, Klein MK, Smith L, Prescott D, Haney S, Looper J, LaDue T, Brawner W, Fidel J, Shiomitsu K, Green E, Saba C, Turek M, Farrelly J:
     A prospective, multi-centre, Veterinary Radiation Therapy Oncology Group study reveals potential efficacy of toceranib phosphate (Palladia) as a primary or adjuvant agent in the treatment of canine nasal carcinoma. Vet Comp Oncol (2021)

  • ・Locker S, Maxwell E, Vilaplana Grosso F, Bertran J, Shiomitsu K:
     Novel treatment of recurrent abdominal lymphatic malformations in a dog. Vet Rec (2021)

  • ・Harding K, De Mello Souza CH, Shiomitsu K, Maxwell E, Bertran J:
     C-KIT, Flt-3, PDGFR-β, and VEGFR2 Expression in Canine Adrenal Tumors and Correlation with Outcome Following Adrenalectomy. Can J Vet Res ;85(4):279-284(2021)

  • ・Fisher CJ, Lejeune AT, Dark MJ, Hernandez OM, Shiomitsu K:
     Evaluation of Ponatinib in vitro Effect in Three Canine Mast Cell Tumor Cell Lines Expressing FGFR-1, PDGFR-α, and VEGFR-2. Vet J ;269:105621(2021)

  • ・Ayers J, Milner RJ, Cortés-Hinojosa G, Riva A, Bechtel S, Sahay B, Cascio M, Lejeune A, Shiomitsu K, Souza C, Hernandez O, Salute M:
     Novel application of single-cell next-generation sequencing for determination of intratumoral heterogeneity of canine osteosarcoma cell lines. J Vet Diagn Invest ;33(2):261-278(2021)

  • ・Shiomitsu K, Bechtel SM, Thompson PM, Frasca S Jr:
     Molecular diagnosis using RNAscope in situ hybridization in canine malignancies. Can J Vet Res ;84(4):319-323(2020)

  • ・Turek M, LaDue T, Looper J, Nagata K, Shiomitsu K, Keyerleber M, Buchholz J, Gieger T, Hetzel S:
     Multimodality treatment including ONCEPT for canine oral melanoma: A retrospective analysis of 131 dogs. Vet Radiol Ultrasound (2020)

  • ・Fox-Alvarez S, Shiomitsu K, Lejeune AT, Szivek A, Kubicek L:
     Outcome of intensity-modulated radiation therapy-based stereotactic radiation therapy for treatment of canine nasal carcinomas. Vet Radiol Ultrasound ;61(3):370-378(2020)

  • ・Sahay B, Aranyos A, Mishra M, McAvoy A, Martin M, Pu R, Shiomitsu S, Shiomitsu K, Dark M, Sanou M, Roff S, Rathore M, Yamamoto J:
     Immunogenicity and Efficacy of a Novel Multi-Antigenic Peptide Vaccine Based on Cross-Reactivity between Feline and Human Immunodeficiency Viruses. Viruses ;11(2):e136(2019)

  • ・Reckelhoff C, Lejeune A, Thompson P, Shiomitsu K:
     In Vitro Effects of the Chemotherapy Agent Water Soluble Micellar Paclitaxel (Paccal Vet) on Canine Hemangiosarcoma Cell Lines. Vet Comp Oncol ;17(1):32-41(2019)

  • ・LaRue M, Brian F, Shiomitsu K:
     Treatment of a Thyroid Tumor in an African Pygmy Hedgehog (Atelerix albiventris). J Exot Pet Med ;25(3):226-230(2016)

  • ・Pagano C, Boudreaux B, Giger G, Ratterree W, Shiomitsu K:
     Coarsely Fractionated Radiation Therapy (10 Gy X 2 Rr.) for the Treatment of Appendicular Osteosarcoma in Dogs. J Am Coll Vet Radiol Ultrasound ;57(5):551-556(2016)

  • ・Cutler D, Shiomitsu K, Neverez J, Bird RT:
     Comparison of Calculated Radiation Delivery Versus Actual Radiation Delivery in Military Macaws (Ara militaris). J Avian Med Surg ;30(1):1-7(2016)

  • ・Jones K, Granger A, Kearney M, da Cunha A, Cutler D, Shapiro M, Tully T, Shiomitsu K:
     Evaluation of a ferret-specific formula for determining body surface area to improve chemotherapeutic dosing. Am J Vet Res ;76(2):142-148(2015)

  • ・Brandão J, Blair R, Kelly A, Fowlkes N, Shiomitsu K, Espinheira F, Rich G, Tully T:
     Amelanotic melanoma in the rabbit: A case report with an overview of immunohistochemical characterization. J Exot Pet Med ;24(2):193-200(2015)

  • ・Gieger T, Siegel S, Rosen K, Jackson D, Ware K, Kiselow M, Shiomitsu K:
     Reirradiation of canine nasal carcinomas treated with coarsely fractionated radiation protocols: 37 cases. J Am Anim Hosp Assoc ;49(5):318-324(2013)

  • ・Mutz M, Boudreaux B, Kearney M, Strouda K, Gaunt S, Shiomitsu K:
     Prognostic value of baseline absolute lymphocyte concentration and neutrophil/lymphocyte ratio in dogs with newly diagnosed multi-centric lymphoma. Vet Comp Oncol ;13(4):337-347(2013)

  • ・Shiomitsu K, Sajo E, Rubin C, Sehgal I:
     The radiosensitizing effect of the aurora kinase inhibitors, ENMD-2076, on canine mast cell tumours in vitro. Vet Comp Oncol ;14(1):13-27(2013)

  • ・Shiomitsu K, Xia X, Sehgal I, Li S:
     Evaluation of aurora kinase inhibitor, ZM447439, in canine malignant lymphoid cells in vitro. Open J Vet Med ;3(1):29-38(2013)

  • ・Gupta A, Garber J, Fowlkes N, Rademacher N, Shiomitsu K, Evans DE, Gaunt SD:
     What is your diagnosis? Abdominal fluid from a dog. Vet Clin Pathol ;42(1):113-114(2012)

  • ・Shiomitsu K, Bauer RW, Grasperge BJ, Suter SE, Waite KJ:
     Cutaneous epitheliotropic lymphoma with dual CD3 and c-kit expression in a dog. Vet Clin Pathol ;41(4):594-598(2012)

  • ・Reed S, Fulmer A, Buckholz J, Cutrera J, Shiomitsu K:
     Bleomycin/interleukin-12 electrochemogenetherapy for treating naturally occurring spontaneous neoplasms in dogs. Cancer Gene Ther ;17(8):571-578(2010)

  • ・Hunley D, Mauldin N, Shiomitsu K:
     Clinical outcome in dogs with nasal tumors treated with intensity-modulated radiation therapy. Can Vet J ;51(3):293-300(2010)

  • ・Shiomitsu K, Johnson CL, Malarkey DE, Pruitt AF, Thrall DE:
     Expression of epidermal growth factor (EGFR) and vascular endothelial growth factor in malignant canine epithelial nasal tumors. Vet Comp Oncol ;7(2):106-114(2009)

  • ・Shiomitsu K, Sajo E, Xia X, Hunley DW, Mauldin GE, Li S, Mauldin GE:
     Radiosensitivity of canine osteosarcoma cells transfected with wild-type p53 in vitro. Vet Comp Oncol ;6(3):193-200(2008)

  • ・Mauldin GN, Shiomitsu K:
     Principles and practice of radiation therapy in exotic and avian species. J Exot Pet Med ;14(3):168-174(2005)

画像診断科

皮膚科

  • ・Hoshino T, Akita T, Sugeno A, Okamura T, Machida Y, Nagata M:
     Long-term follow-up of a single dose of fluralaner in nine dogs with canine demodicosis. Vet Dermatol ;32:368-e102(2021)