Yoshihiko Yu,Daisuke Hasegawa,Shinichi Kanazono,Miyoko Saito, Clinical characterization of epileptic seizures in Pomeranians with idiopathic epilepsy or epilepsy of unknown cause 2022

Rebecca Stevens, Shinichi Kanazono, DVM, Scott Petesch, Ling T. Guo, MD, PhD; G. Diane Shelton, Dystrophin-Deficient Muscular Dystrophy in Two Male Juvenile Brittanys 2022

Shinichi Kanazono, Masayasu Ukai and Akira Hiramoto. Abnormal Behavior Episodes Associated With Zonisamide in Three Dogs: A Case Report. 2021

Daisuke Hasegawa, Rikako Asada, Satoshi Mizuno, Yoshihiko Yu, Yuji Hamamoto and Shinichi Kanazono. Case Report: Corpus Callosotomy in a Cat with Drug-Resistant Epilepsy of Unknown Cause.2021

Spoor MS, Kim DY, Kanazono S, Wininger FA, Whitney MS (2013) “What is your diagnosis? Cerebral mass impression smears from a dog” J Vet Clin Pathol 42:240-241.2021

Aikawa T, Fujita H, Kanazono S, Shibata M, Yoshigae Y. Long-term neurologic outcome of hemilaminectomy and disk fenestration for treatment of dogs with thoracolumbar intervertebral disk herniation: 831 cases. JAVMA 241:1617-1626.2012

Vuillemenot BR, Katz ML, Coates JR, Kennedy D, Tiger P, Kanazono S, Lobel P, Sohar I, Xu S, Cahayag R, Keve S, Koren E, Bunting S, Tsuruda LS, O’Neill CA. “Intrathecal tripeptidyl-peptidase I reduces lysosomal storage in a canine model of late infantile Neuronal Ceroid Lipofuscinosis” Molecular Genetics and Metabolism 104:325-337.2011

Sanders DN, Kanazono S, Wininger FA, Whiting R, Flournoy C, Coates JR, Castaner L, O’Brien DP, Katz ML. “A reversal learning task detects early cognitive deficits in a dachshund model of late-infantile neuronal ceroid lipofuscinosis” Genes, Brain, and Behavior 10:798-804.2011

Sanders DN, Kanazono S, Coates JR, Johnson GS, Johnson GC, Narfstrom K, O'Brien DP, Katz ML.

Kanazono S, Aikawa T, Yoshigae Y. “Unilateral hydronephrosis and partial ureteral obstruction by entrapment in a granuloma in a spayed dog.” J Am Anim Hosp Assoc 45:301-304.2009

Aikawa T, Yoshigae Y, Kanazono S. “Epidural idiopathic sterile pyogranulomatous inflammation causing spinal cord injury in five miniature dachshunds.” Veterinary Surgery 37:594-601.2008

Aikawa T, Kanazono S, Yoshigae Y, Sharp NJH, Muñana KR “Vertebral Stabilization Using Positively Threaded Profile Pins and Polymethylmethacrylate, with or without Laminectomy, for Spinal Canal Stenosis and Vertebral Instability Caused by Congenital Thoracic Vertebral Anomalies.” Veterinary Surgery 36:432-441.2007

Mizuno T, Mizuno M, Harada K, Takano H, Shinoda A, Takahashi A, Mamada K, Takamura K, Chen A, Iwanaga K, Ono S, Uechi M. Surgical correction for sinus venosus atrial septal defect with partial anomalous pulmonary venous connection in a dog. Journal of Veterinary Cardiology, 2020;28:23-30.

Takano H, Kokubu A, Sugimoto K, Sunahara H, Aoki T, Fujii Y. Left ventricular structural and functional abnormalities in dogs with hyperadrenocorticism. Journal of Veterinary Cardiology. 2015;17:173-181.

Takano H, Isogai T, Aoki T, Wakao Y, Fujii Y. Feasibility of Radial and Circumferential Strain Analysis Using 2D Speckle Tracking Echocardiography in Cats. The journal of veterinary medical science. 2015;77(2):193–201.

Ishikawa R, Fujii Y, Takano H, Sunahara H, Aoki T, Wakao Y. Left Ventricular Reverse Remodeling After Ductal Closure in Dogs with Hemodynamically Significant Patent Ductus Arteriosus. The internatinal journal of applied research in veterinary medicine. 2013;11(1):66-69.

Aoki T, Fujii Y, Sunahara H, Takano H, Wakao Y. Modified loop technique in three dogs with mitral regurgitation. The Journal of veterinary medical science. 2013;75:107-11.

Fujii Y, Nishimoto Y, Sunahara H, Takano H, Aoki T. Prevalence of patent foramen ovale with right-to-left shunting in dogs with pulmonic stenosis. Journal of veterinary internal medicine. 2012;26:183-5.

Takano H, Fujii Y, Yugeta N, Takeda S, Wakao Y. Assessment of left ventricular regional function in affected and carrier dogs with Duchenne muscular dystrophy using speckle tracking echocardiography. BMC cardiovascular disorders. 2011;11:23.

Takano H, Fujii Y, Ishikawa R, Aoki T, Wakao Y. Comparison of left ventricular contraction profiles among small, medium, and large dogs by use of two-dimensional speckle-tracking echocardiography. American journal of veterinary research. 2010;71:421-7.

Fujii Y, Aoki T, Takano H, Ishikawa R and Wakao Y. Arteriovenous shunts resembling patent ductus arteriosus in dogs: 3 cases. Journal of veterinary cardiology. 2009;11:147-51.

Azuma, K., Asakawa, M, Konno, T., Fukuda, S., Goto Asakawa M. Hypoglycemia associated with disseminated metastatic tonsillar squamous cell carcinoma producing insulin-like growth factor-I in a Pomeranian dog. Veterinary Clinical Pathology. 2019. 48; 429-434.

Mitsui A, Selmic LE et al: Hypercoagulability based on thromboelastography is common in dogs undergoing adrenalectomy. (JAVMA, accepted Feb 2024)

Gilson SD, Lillian R, Mitsui A, “Adrenalectomy”. Current Techniques in Small Animal Surgery 5th Edition. Ed. M Joseph Bojrab. Jackson: Teton New Media, 2014

Mitsui A, Mathews KG et al: Effects of Fascial Abrasion, Fasciotomy, and Fascial Excision on Cutaneous Wound Healing in Cats. Am J Vet Res 2009 Apr;70(4):532-8


M. Akiyoshi, M. Hisasue, Y. Goto-Koshino, M.G. Asakawa, S. Neo, M. Akiyoshi, H. Tomiyasu
Clinicopathologic findings of splenic marginal zone lymphoma with gallbladder involvement that progressed to diffuse large B cell lymphoma in a dog. Vet Clin Pathol, 2024 manuscript in press.

M.G. Asakawa, CA Jamieson, D Florent, JP Johnson, M W Mehmood, MA Oikawa
CD3+ T-Lymphocytic Coeliac-Mesenteric Ganglioneuritis Associated with Colonic Torsion and Inflammatory Bowel Disease in an Arabian Broodmare J Comp Pathol. 2022 194:1-6 doi: 10.1016/j.jcpa.2022.03.002.

M.Akiyoshi, M. Hisasue, M.G. Asakawa, S. Neo, M. Akiyoshi.
Hepatosplenic lymphoma and visceral mast cell tumor in the liver: synchronous multiple primaries in a dog. Vet Clin Pathol. 2022 51:414-421. doi: 10.1111/vcp.13086.

A Ueyama, T Hoshino, M.G. Asakawa, T Shimada , M Nagata.
Focal cutaneous telangiectasia in a young dog of probable congenital origin. Vet Med Sci, 2022 8:2277-2282. doi: 10.1002/vms3.940.

DJ. Meuten, FM. Moore, TA. Donovan, CA. Bertram, R. Klopfleisch, RA. Froster, RC. Smedley, MJ. Dark, M. Milovancev, P. Stromberg, BH. Williams, M. Aubreville, G. Avallone, P. Blolfa, JM. Cullen, MM. Dennis, M. Goldschmidt, R. Loung, AD. Miller, MA. Miller, JS. Munday, P. Roccabianica, EN. Salas, FY . Schulman, R. Laufer-Amorim, M.G. Asakawa, L. Craig, N. Dervisis, DG. Esplin, JW. M. Hauck, Y. Kagawa, M. Kiupel, K. Linder, K. Meichner, L. Marconato, ML. Oblack, RL. Santos, RM. Simpson, H. Tvedten, D. Whitley.
International Guidelines for Veterinary Tumor Pathology: A Call to Action. Vet Pathol. 2021, 58:766-794.

M. Asakawa, M. Fukuzawa, M.G. Asakawa, JA. Flanders.
Preoperative serum C-reactive protein concentration can be used to detect gallbladder rupture in dogs with gallbladder mucocele. Am J Vet Res. 2022 Jan 1:1-10. doi: 10.2460/ajvr.21.09.0141.

K. Enomoto, C. Tsutsumitani, and M.G. Asakawa.
Clinicopathologic, Immunohistochemical, and Ultrastructural Features of Histiocytic Sarcoma in a Chinchilla (Chinchilla lanigera). Vet Med Sci, 2021.

M.G. Asakawa, W. Mehmood, A. Mohammad, M. Oikawa.
Idiopathic Multifocal Myocardial Atrophy with Fibrosis and Fatty Infiltration Involving Purkinje Fibers in a 13-year-old Arabian Broodmare: Histopathological Features. Vet Med Sci.2021;7:3–8.

I. Koizumi, D. Hernandez-Muguiro, S.A.A. Chu, T. Stokol, M.G. Asakawa
Clinicopathologic Findings of Spontaneous Leukemia in 9 Pet African Hedgehogs (Atelerix albiventris) Front Vet Sci, 2020 7:54.

K. Azuma, M. Asakawa, T. Konno, S. Fukuda, M.G. Asakawa
Hypoglycemia Associated with Disseminated Metastatic Tonsillar Squamous Cell Carcinoma Producing Insulin-like Growth Factor-I in a Pomeranian Dog. Vet Clin Pathol. 2019 48: 429-434.

A. Newman, M.G. Asakawa, and T. Stokol.
What’s Your Diagnosis? Mandibular mass in a Cat. Vet Clin Pathol. 2018 47:501-502.

E. A. Barrel, M.G. Asakawa, M.J.B Felippe, T.J. Divers, T Stokol.
Acute Leukemia in Six Horses (1990-2012). J Vet Diagn Invest. 2017 29:529-535.

M.G. Asakawa, S Lewis, E Buckles, T Stokol
What’s Your Diagnosis? Granular Cell Type Trichoblastoma in a Dog. Vet Clin Pathol. 2015 44:607-608.

C. Picut, A. Remick, M.G. Asakawa, M.L. Simons, G.A. Parker.
Histologic Features of Prepubertal and Pubertal Reproductive Development in Female Sprague Dawley Rats. Toxcologic Pathol. 2014 42:403-4013.

M. G. Asakawa, J.M. Cullen, and K.E. Linder.
Necrolytic Migratory Erythema Associated with a Glucagon-Producing Primary Hepatic Neuroendocrine Carcinoma in a Cat. Vet Dermatol. 2013 24:466-469

M. G. Asakawa, M. K. Ames, and Y. Kim.
Primary Cardiac Spindle Cell Tumor in a Dog. Can Vet J. 2013 54:672-674.

E. T. Anderson, S. Frasca Jr, M. G. Asakawa, M. H. Falzinger, J Johnson, K. Marchettere, L. Goodale, G. R. Risatti and C.A. Harms.
Splenic Mycobacteriosis in an Atlantic guitar fish, Rhinobatos lentiginosus Garman. 2012 35:541-544

M. G. Asakawa
Introduction to Gross Pathology of Hepatobiliary Diseases in Dogs and Cats. Review. Jap J Vet Clin Path. 2012 1:1-16

M. G. Asakawa, E. Mackillop, N. Olby, I. D. Robertson, and J. M. Cullen.
Neuronal Ceroid Lipofuscinosis with a Chronic Subdural Hematoma. Vet Radiol Ultrasound.. 2010 51:155-158

M. G. Asakawa, M. H. Goldschmidt, Y. Une, and Y. Nomura.
The Immunohistochemical Evaluation of Estrogen and Progesterone Receptors of Normal, Hyperplastic and Neoplastic Endometrium in 88 Pet Rabbits. Vet Pathol. . 2008 45:217-225

M. Goto (Asakawa), Y. Nomura, Y. Une, and M. H. Goldschmidt.
Malignant Mixed Müllerian Tumor in a Rabbit (Oryctolagus cuniculus): Case Report with Immunohistochemistry. Vet Pathol. 2006 43: 560-564


Sato M, Shropshire SB, Veir JK, Lappin MR. Ehrlichia canis, in dogs experimentally infected, treated, and then immune suppressed during the acute or subclinical phases., J Vet Intern Med., 34;1214-1221, 2020

Graham JA, Sato M, Moor AR, McGrew AK, Ballweber LR, Byas AD, Dowers KL.
Strongyloides stercoralis disseminated infection in a dog treated with budesonide
J Am Vet Med Assoc., 254;974-978, 2019

Sato M, Mochizuki H, Goto-Koshino Y, Fujiwara-Igarashi A, Takahashi M, Ohno
K, Tsujimoto H. Prognostic significance of hypermethylation of death-associated
protein kinase(DAPK) gene CpG island in dogs with high-grade B-cell lymphoma.
Vet Comp Oncol., 16;409-415, 2018

Sato M, Veir JK, Legare M, Lappin MR. A retrospective study on the safety and
efficacy of leflunomide in dogs. J Vet Intern Med., 31;1502-1507, 2017.

Sato M, Yamazaki J, Goto-Koshino Y, Setogushi A, Takahashi M, Baba K, Fujino
Y, Ohno K, Tsujimoto H. Minimal residual disease in canine lymphoma: an objective
marker to assess tumor cell burden in remission. Review. Vet J., 215:38-42, 2016

Sato M, Mochizuki H, Goto-Koshino Y, Fujiwara-Igarashi A, Takahashi M, Fujino
Y, Ohno K, Tsujimoto H. Hypermethylation of the death-associated protein kinase
CpG island in dogs with canine B-cell lymphoid tumors. Vet Immunol Immunopathol.,
161:222-231, 2014

Sato M, Storb R, Loretz C, Stone D, Mielcarek M, Sale GE, Rezvani AR, Graves
SS. Inducible costimulatory (ICOS) up-regulation on activated T-cells in chronic
graft-versus-host disease after dog leukocyte antigen-nonidentical hematopoietic
cell transplantation: a potential therapeutic target. Transplantation, 96:34-41,

Sato M, Yamazaki J, Goto-Koshino Y, Takahashi M, Fujino Y, Ohno K, Tsujimoto
H. The prognostic significance of minimal residual disease in the early phases
of chemotherapy in dogs with high-grade B-cell lymphoma. Vet J., 195:319-324, 2012

Sato M, Kanemoto H, Kagawa Y, Kobayashi T, Goto-Koshino Y, Mochizuki H,
T5kahashi M, Fujino Y, Ohno K, Tsujimoto H. Evaluation of prognostic significance
of BCL6 gene expression in canine high-grade B-cell lymphoma. Vet J., 191:108-114,

Sato M, Yamazaki J, Takahashi M, Goto-Koshino Y, Fujino Y, Ohno K, Tsujimoto
H. Evaluation of cytoreductive efficacy of vincristine, cyclophosphamide, and
doxorubicin in dogs with lymphoma by measuring the number of neoplastic lymphoid
cells with real-time polymerase chain reaction. J Vet Intern Med., 25:285-291,

Sato M, Yamazaki J, Takahashi M, Goto-Koshino Y, Fujino Y, Ohno K, Tsujimoto
H. Increase in minimal residual disease (MRD) in peripheral blood before clinical
relapse in dogs with lymphoma that achieved complete remission after chemotherapy.
J Vet Intern Med., 25:292-296, 2011

Sato M, Goto-Koshino Y, Mochizuki H, Fujino Y, Ohno K, Tsujimoto H. Perfusion
method for harvesting bone marrow cells from dogs. Am J Vet Res., 72:1344-1348,

Sato M, Goto-Koshino Y, Kanemoto H, Mochizuki H, Fujino Y, Ohno K, Tsujimoto
H. Characterization of canine BCL6 cDNA and detection systems for its protein
expression. Vet Immunol Immunopathol., 140:166-169, 2011

Fukushima K, Lappin M, Legare M, Veir J. A retrospective study of adverse effects of mycophenolate mofetil administration to dogs with immune-mediated disease. J Vet Intern Med. 2021 Sep;35(5):2215-2221.

Kanemoto Y, Fukushima K, Kanemoto H, Ohno K, Tsujimoto H. Long-term management of a dog with idiopathic megaesophagus and recurrent aspiration pneumonia by use of an indwelling esophagostomy tube for suction of esophageal content and esophagogastric tube feeding. J Vet Med Sci. 2017 Jan 24;79(1):188-191.

Fukushima K, Eguchi N, Ohno K, Kanemoto H, Takahashi M, Igarashi H, Ohmi A, Nakashima K, Tsujimoto H. Efficacy of leflunomide for treatment of refractory inflammatory colorectal polyps in 15 Miniature Dachshunds. J Vet Med Sci. 2016 Feb;78(2):265-9.

Fukushima K, Fujiwara R, Yamamoto K, Kanemoto H, Ohno K, Tsuboi M, Uchida K, Matsuki N, Nishimura R, Tsujimoto H. Characterization of triple-phase computed tomography in dogs with pancreatic insulinoma. J Vet Med Sci. 2016 Jan;77(12):1549-53.

Fukushima K, Kanemoto H, Ohno K, Takahashi M, Fujiwara R, Nishimura R, Tsujimoto H. Computed tomographic morphology and clinical features of extrahepatic portosystemic shunts in 172 dogs in Japan. Vet J. 2014 Mar;199(3):376-81.

Fukushima K, Kanemoto H, Ohno K, Takahashi M, Nakashima K, Fujino Y, Uchida K, Fujiwara R, Nishimura R, Tsujimoto H. CT characteristics of primary hepatic mass lesions in dogs. Vet Radiol Ultrasound. 2012 May-Jun;53(3):252-7.

Fukushima K, Ohno K, Koshino-Goto Y, Uchida K, Nomura K, Takahashi M, Nakashima K, Fujino Y, Tsujimoto H. Sensitivity for the detection of a clonally rearranged antigen receptor gene in endoscopically obtained biopsy specimens from canine alimentary lymphoma. J Vet Med Sci. 2009 Dec;71(12):1673-6.

Fukushima K, Okai Y, Matsuura S, Tsujimoto H, Endo Y. Molecular cloning of feline lung resistance-related protein (LRP) cDNA and its expression in a feline lymphoma cell line and adriamycin-resistant subline. J Vet Med Sci. 2006 Aug;68(8):885-90.


Yoshikawa H, Lafferty MH, Griffin LR, LaRue SM.A retrospective study of sinonasal tumors in 182 dogs treated with stereotactic radiotherapy (3 x 10 Gy)(2010-2015). J Vet Intern Med, 37(6): 2356-2367, 2023.

Carlos H De Mello Souza, Keijiro Shiomitsu , Benjamin Hwang. Cytokine production and the Effects of Oclacitinib in Three Canine Mast Cell Tumor Cell Lines. Veterinary Dermatology. Vet Dermatol. 2022 Apr;33(2). doi: 10.1111/vde.13046. Epub 2021 Dec 9.

Julia L Engelien, Amandine T Lejeune, Frasca Salvatore Jr., Michael J Dark, Rowan Milner, Oscar Hernandez, Keijiro Shiomitsu . RNA in situ Hybridization as a Molecular Diagnostic Technique Targeting IBA-1 and CD204 in Canine Histiocytic Sarcoma. Veterinary Comparative Oncology. Accepted. Jan 2022.

Ackerman LH, de Mello Souza CH, Cortés-Hinojosa G, Salute ME, Stephen AA, Anthony E, Shiomitsu K , Milner RJ. Identification of the interleukin-8 (CXCL-8) pathway in feline oral squamous cell carcinoma - A pilot study. Can J Vet Res. 2022 Jan;86(1):13-19.

Ehling TJ, Klein MK, Smith L, Prescott D, Haney S, Looper J, LaDue T, Brawner W, Fidel J, Shiomitsu K , Green E, Saba C, Turek M, Farrelly J. A prospective, multi-centre, Veterinary Radiation Therapy Oncology Group study reveals potential efficacy of toceranib phosphate (Palladia) as a primary or adjuvant agent in the treatment of canine nasal carcinoma. Vet Comp Oncol. 2021 Oct 16. doi: 10.1111/vco.12776. Online ahead of print.

Locker, Seth; Maxwell, Elizabeth; Vilaplana Grosso Federico; Bertran Judith; Shiomitsu Keijiro . Novel treatment of recurrent abdominal lymphatic malformations in a dog. Veterinary Record. Online first published: 15 June 2021

Kayla Harding, Carlos H De Mello Souza, Keijiro Shiomitsu , Elizabeth Maxwell, Judit Bertran. C-KIT, Flt-3, PDGFR-β, and VEGFR2 Expression in Canine Adrenal Tumors and Correlation with Outcome Following Adrenalectomy. Can J Vet Res. 2021 Oct;85(4):279-284.

Fisher CJ, Lejeune AT, Dark MJ, Hernandez OM, Shiomitsu K . Evaluation of Ponatinib in vitro Effect in Three Canine Mast Cell Tumor Cell Lines Expressing FGFR-1, PDGFR-α, and VEGFR-2. Vet J. 2021 Mar;269:105621. doi: 10.1016/j.tvjl.2021.105621. Epub 2021 Jan 19.

Ayers J, Milner RJ, Cortés-Hinojosa G, Riva A, Bechtel S, Sahay B, Cascio M, Lejeune A, Shiomitsu K , Souza C, Hernandez O, Salute M. Novel application of single-cell next-generation sequencing for determination of intratumoral heterogeneity of canine osteosarcoma cell lines. Journal of Veterinary Diagnostic investigation. J Vet Diagn Invest. 2021 Mar;33(2):261-278. doi: 10.1177/1040638720985242. Epub 2021 Jan 15.

Shiomitsu, K . Bechtel SM, Thompson PM, Frasca, S, Jr. Molecular diagnosis using RNAscope in situ hybridization in canine malignancies, Canadian Journal of Veterinary Research, 2020 Oct;84(4):319-323.

Turek M, LaDue T, Looper J, Nagata K, Shiomitsu K , Keyerleber M, Buchholz J, Gieger T, Hetzel S. Multimodality treatment including ONCEPT for canine oral melanoma: A retrospective analysis of 131 dogs. Vet Radiol Ultrasound. 2020 Apr 22. doi: 10.1111/vru.12860.

Fox-Alvarez S, Shiomitsu K , Lejeune AT, Szivek A, Kubicek L., Outcome of intensity-modulated radiation therapy-based stereotactic radiation therapy for treatment of canine nasal carcinomas. Vet Radiol Ultrasound. 2020 May;61(3):370-378. doi: 10.1111/vru.12854. Epub 2020 Mar 18.

Sahay, B., Aranyos, A., Mishra, M., McAvoy, A., Martin, M., Pu, R., Shiomitsu, S., Shiomitsu, K ., Dark, M., Sanou, M., Roff, S., Rathore, M., Yamamoto, J. Immunogenicity and Efficacy of a Novel Multi-Antigenic Peptide Vaccine Based on Cross-Reactivity between Feline and Human Immunodeficiency Viruses. Viruses. 2019 Feb 3;11(2). pii: E136.

Reckelhoff, C., Lejeune, A., Thompson, P., Shiomitsu, K . In Vitro Effects of the Chemotherapy Agent Water Soluble Micellar Paclitaxel (Paccal Vet) on Canine Hemangiosarcoma Cell Lines, Veterinary Comparative Oncology, 2019 Mar;17(1):32-41.

LaRue, M., Brian, F., Shiomitsu, K . Treatment of a Thyroid Tumor in an African Pygmy Hedgehog (ATELERIX ALBIVENTRIS), Journal of Exotic Pet Medicine, 2016 July;25(3): 226-30.

Pagano, C., Boudreaux, B., Giger, G., Ratterree, W., Shiomitsu, K . Coarsely Fractionated Radiation Therapy (10 Gy X 2 Rr.) for the Treatment of Appendicular Osteosarcoma in Dogs. Journal of American College of Veterinary Radiology and Ultrasound. 2016 Sep;57 (5): 551-6.

Cutler, D, Shiomitsu, K . Neverez, J. Bird RT. Comparison of Calculated Radiation Delivery Versus Actual Radiation Delivery in Military Macaws (Ara militaris). Journal of Avian Medicine and Surgery. 2016 Mar;30(1):1-7.

Jones, K., Granger, A., Kearney, M., da Cunha, A., Cutler, D., Shapiro, M., Tully, T., Shiomitsu, K . Evaluation of a ferret-specific formula for determining body surface area to improve chemotherapeutic dosing (2015) American Journal of Veterinary Research. 76(2):142-8.

Brandão, J., Blair, R., Kelly, A., Fowlkes, N., Shiomitsu, K . Espinheira, F., Rich, G., Tully, T. Amelanotic melanoma in the rabbit: A case report with an overview of immunohistochemical characterization. Journal of Exotic Pet Medicine (2015) Volume 24, Issue 2, Pages 193–200

Gieger, T., Siegel, S., Rosen, K., Jackson, D., ¥Ware, K., Kiselow, M., Shiomitsu, K . Reirradiation of canine nasal carcinomas treated with coarsely fractionated radiation protocols: 37 cases. Journal of the American Animal Hospital Association (2013) Sep-Oct,49(5);318-24.

Mutz, M., Boudreaux, B., Kearney, M., Strouda, K., Gaunt, S., Shiomitsu, K . (2013) Prognostic value of baseline absolute lymphocyte concentration and neutrophil/lymphocyte ratio in dogs with newly diagnosed multi-centric lymphoma. Veterinary Comparative Oncology, Dec;13(4):337-47

Shiomitsu K ., Sajo, E., Rubin, C., Sehgal, I. (2013) The radiosensitizing effect of the aurora kinase inhibitors, ENMD-2076, on canine mast cell tumours in vitro. Veterinary Comparative Oncology, Mar;14(1):13-27

Shiomitsu, K ., Xia, X., Sehgal I., Li S. (2013) Evaluation of aurora kinase inhibitor, ZM447439, in canine malignant lymphoid cells in vitro. Open Journal of Veterinary Medicine, 3 (1), 29-38.

Gupta, A., Garber, J., Fowlkes, N., Rademacher, N., Shiomitsu, K . , Evans, D.E., Gaunt, S.D. (2012) What is your diagnosis? Abdominal fluid from a dog. Veterinary Clinical Pathology, 42 (1), 113-114.

Shiomitsu, K ., Bauer, R.W., Grasperge, B.J., Suter, S.E., Waite, K.J. (2012) Cutaneous epitheliotropic lymphoma with dual CD3 and c-kit expression in a dog. Veterinary Clinical Pathology, 41(4), 594-598.

Reed, S., Fulmer, A., Buckholz, J., Cutrera, J., Shiomitsu, K. (2010) Bleomycin/interleukin-12 electrochemogenetherapy for treating naturally occurring spontaneous neoplasms in dogs. Cancer Gene Therapy, 17(8), 571-578.

Hunley, D., Mauldin, N., Shiomitsu, K . (2010) Clinical outcome in dogs with nasal tumors treated with intensity-modulated radiation therapy. Canadian Veterinary Journal, 51(3), 293-300.

Shiomitsu, K ., Johnson C.L., Malarkey, D.E., Pruitt, A.F., Thrall, D.E., (2009) Expression of epidermal growth factor (EGFR) and vascular endothelial growth factor in malignant canine epithelial nasal tumors. Veterinary Comparative Oncology, 7(2), 106-114.

Shiomitsu, K ., Sajo, E., Xia, X., Hunley, D,W., Mauldin G,E., Li, S., Mauldin G,E. (2008) Radiosensitivity of canine osteosarcoma cells transfected with wild-type p53 in vitro. Veterinary Comparative Oncology, 6(3), 193-200.

Mauldin, G.N., Shiomitsu K . (2005) Principles and practice of radiation therapy in exotic and avian species. Journal of Exotic Pet Medicine, 14(3), 168-174.

Nolan MW, Berman AR, Watson-Skaggs W, Quinn CN, Marcus KL, Russell K, Yoshikawa H, Olby NJ, Gieger TG. Stereotactic radiotherapy (10 Gy x 3) for canine non-lymphomatous intranasal tumors is associated with prolonged survival and minimal risk of severe radiotoxicity. Journal of the American Veterinary Medical Association. In press

Watson ML, Gieger TL, Yoshikawa H (corresponding author), Nolan MW. Endocrine response and outcome in 14 cats with insulin resistance and acromegaly treated with stereotactic radiosurgery (17 Gy). Am. J. Vet. Res., 83 (1): 64-71, 2021.

Yoshikawa H, Gieger TL, Saba CF, Frederickson K, Kubicek L, Haney S, Ruslander D, Kelsey K, McEntee MC, Nolan MW. Retrospective evaluation of feline intranasal carcinoma treated with external-beam radiotherapy; 42 cases. J Vet Int Med, doi: 10.1111/jvim.16098, 2021.

Richard AG, Yoshikawa H (corresponding author), Palmer GM, Liu HQ, Dewhirst MW, Nolan MW, Zhang X. Cherenkov emission for studying tumor changes during radiation therapy: an exploratory study in domesticated dogs with naturally-occurring cancer. PLoS One. 15(8): e0238106.. eCollection 2020.

Sweet KA, Nolan MW, Yoshikawa H (corresponding author), Gieger TL. Stereotactic radiation therapy for canine multilobular osteochondrosarcoma: 8 cases. Vet. Comp. Oncol., 18(1): 76-83, 2020.

Yoshikawa H, Sunada S, Hirakawa H, Fujimori A, Elmegerhi S, Leary D, Kato T. Radiobiological characterization of canine malignant melanoma cell lines with different types of ionizing radiation and efficacy evaluation with cytotoxic agents. Int. J. Mol. Sci., 20(4); 841, 2019.

Yoshikawa H, Nolan MW. Changes in target volume during irradiation of canine intranasal tumors can significantly impact radiation dosimetry. Vet. Radiol. Ultrasound, 60; 594-604, 2019.

Yoshikawa H, Maranon DG, Battaglia, CLR, Ehrhart EJ, Charles JB, Bailey SM, LaRue SM. Predicting clinical outcome in feline oral squamous cell carcinoma: tumor initiating cells, telomeres, and telomerase. Vet Comp Oncol, 2016 Dec 14(4):371-383.

Randall EK, Kraft SL, Yoshikawa H, LaRue SM. Evaluation of 18F-FDG PET/CT as a diagnostic imaging and staging tool for feline oral squamous cell carcinoma. Vet Comp Oncol, 14(1):28-38, 2016. doi: 10.1111/vco.12047.

Yoshikawa H, Ehrhart EJ, Charles BJ, LaRue SM. Assessment of predictive variables in feline oral squamous cell carcinoma treated with stereotactic radiation therapy. Vet Comp Oncol, 2016 Mar; 14(1):39-57.

Yoshikawa H, Nolan MW, Lewis D, LaRue SM. Retrospective evaluation of inter-fraction ureteral movement in dogs undergoing radiation therapy. Vet Radiol Ultrasound, 57; 170-179, 2015.

Yoshikawa H, Roback DM, LaRue SM, Nolan MW. Dosimetric consequences of using contrast-enhanced CT images for intensity-modulated stereotactic body radiation therapy planning. Vet Radiol Ultrasound, 56; 687-695, 2015.

Nolan WM, Marolf AJ, Ehrhart EJ, Rao S, Kraft SL, Engel S, Yoshikawa H, Golden AE, Wasserman TH, LaRue SL. Pudendal nerve and internal pudendal artery damage may contribute to radiation-induced erectile dysfunction. Int J Radiation Oncol Bio Phys, 91;796-806, 2015.

Randall EK, Yoshikawa H, Kraft SL, LaRue SM. A translational feline model of oral squamous cell carcinoma for evaluating tumor volume delineation with PET/CT. Pract Radia Oncol, doi: 10.1016/j.prro.2013.01.099.

Yoshikawa H, Randall EK, Kraft SL, LaRue SM. Comparison between 2-18F-fluoro-2-deoxy-D-glucose positron emission tomography and contrast-enhanced computed tomography for measuring gross tumor volume in cats with oral squamous cell carcinoma. Vet. Radiol. Ultrasound, 54; 307-313, 2013.

Harmon JF, Yoshikawa H, Custis J, LaRue S. Evaluation of Canine Prostate Intrafractional Motion Using Serial Cone Beam CT Imaging. Vet. Radiol. Ultrasound, 54; 93-98, 2013.

Yoshikawa H, Harmon JF, LaRue SM. Repeatability of a planned target volume expansion protocol for radiation therapy of regional lymph nodes in canine and feline patients with head tumors. Vet. Radiol. Ultrasound, 53; 667-672, 2012.

Yoshikawa H, Ehrhart EJ, Charles BJ, Thamm DH, LaRue SM. Immunohistochemical characterization of feline oral squamous cell carcinoma. Am. J. Vet. Res, 73; 1801-1806, 2012.

Mayer MN, Yoshikawa H, Sidhu N. Impact of tissue inhomogeneity on dose distribution in the canine carpal and tarsal regions for cobalt and 6MV photons. Vet. Radiol. Ultrasound, 50(3); 319-322, 2009.

Mayer MN, Yoshikawa H, Moriarity L, Sidhu N. Use of a petroleum based bolus for photon radiation therapy of distal extremities in dogs. Vet. Radiol. Ultrasound, 50(2); 235-238, 2009.

Yoshikawa H, Mayer MN. External beam radiation therapy for canine intracranial meningioma. Can. Vet. J. 50(1); 97-100, 2009.

Mayer MN, Grier CK, Yoshikawa H, Ringwood BR. Complications associated with the use of vascular access ports in dogs undergoing curative external beam radiation therapy. J. Am. Vet. Med. Assoc. 233(1); 96-103, 2008.

Yoshikawa H, Mayer MN, Linn KA, Dickinson RM, Carr, T. A dog with squamous cell carcinoma in the middle ear. Can. Vet. J. 49(8); 877-879, 2008.

Yoshikawa H, Nakamoto Y, Ozawa T, Dickinson RM. A dog with osteosarcoma which metastasized to the eye months before metastasis to other organs. J. Vet. Med. Sci., 70(8); 825-828, 2008.

Yoshikawa H, Watanabe K, Ozawa T. Odontoclastic resorptive lesions in a dog. J. Vet. Med. Sci., 70 (1); 103-105, 2008.


Fukuda, S, Reetz, JA, Hamamoto, K, Griffin, L, Schaffer, PA. Diagnostic imaging and histopathologic features of rounded atelectasis in four cats and one dog: A descriptive case series study. Vet Radiol Ultrasound.. 2022; 1- 9.

Fukuda, S., Kobayashi, T., Robertson, I.D., Oshima, F., Fukazawa, E., Nakano, Y., Ono, S. and Thrall, D.E. (2014), COMPUTED TOMOGRAPHIC FEATURES OF CANINE NONPARENCHYMAL HEMANGIOSARCOMA.. Vet Radiol Ultrasound, 55: 374-379.

Azuma, K, Asakawa, M, Konno, T, Fukuda, S, Goto Asakawa, M. Hypoglycemia associated with disseminated metastatic tonsillar squamous cell carcinoma producing insulin-like growth factor-I in a Pomeranian dog. Vet Clin Pathol. 2019; 48: 429– 434.

Hoshino, T., Fukuda, S., & Nagata, M. (2022). Diode laser-assisted transcanal endoscopic removal of an aural polyp in the external auditory canal of a dog. Veterinary Medicine and Science, 8, 1862– 1866.

Miki S, Akiyama Yamashita K, Kanzaki Okamoto M, Iwanaga Y, Fukuda S, Mashita T. Chronic spinal epidural abscess in a cat: a case report with an unusual imaging finding. J Vet Med Sci. 2022 Jan 7;84(1):69-73. doi: 10.1292/jvms.21-0462. Epub 2021 Nov 29. PMID: 34840200; PMCID: PMC8810312.


Azuma, K., Ohmi,、A., Goto-Koshino, Y., Tomiyasu, H., Ohno, K., Chambers, James K., Uchida, K., Namba, H., Nagata, M, Nagamine, E., Nibe, K., Irie、M., Tsujimoto, H. Outcomes and prognostic factors in canine epitheliotropic and non-epitheliotropic cutaneous T-cell lymphomas. Vet Com Oncol. 2021. In press

Hoshino, T., Akita, T., Sugeno, A., Okamura, T., Machida, Y., Nagata, M. Long-term follow-up of a single dose of fluralaner in nine dogs with canine demodicosis. Vet Dermatol. 32: 368-e102, 2021.

Hoshino, T., Akita, T., Sugeno, A., Okamura, T., Machida, Y., Nagata, M. Long-term follow-up of a single dose of fluralaner in nine dogs with canine demodicosis. Vet Dermatol. In press

Asahina, R., Ueda, K., Oshima, Y., Kanei, T., Kato, M., Furue, M., Tsukui, T., Nagata, M., Maeda, S. Serum canine thymus and activation-regulated chemokine (TARC/CCL17) concentrations correlate with disease severity and therapeutic responses in dogs with atopic dermatitis. Vet Dermatol. 31: 439-e116, 2020.

Imai, A., Kondo, H., Suganuma, T., Nagata, M. Clinical analysis and nonsurgical management of 11 dogs with aural cholesteatoma. Vet Dermatol. 30: 42-e12, 2019.

Ueda K., Kawai, T., Senoo, H., Shimizu, A., Ishiko, A., Nagata, M. Histopathological and electron microscopic study in dogs with patellar luxation and skin hyperextensibility. J. Vet. Med. Sci. 80:1309-1316, 2018.

Kondo, H., Kagawa, Y., Shirota, K., Moore, P.F., Nagata, M. Canine non-epitheliotropicCD4-positive cutaneous T-cell lymphoma: a case report Vet Med Sci. 2018. Dec 12.

Ohshima-Terada, Y. Higuchi, Y. Kumagai, T., Hagihara, A., Nagata, M. Complementary effect of oral administration of Lactobacillus paracasei K71 on Canine Atopic Dermatitis. Vet Dermatol. 26: 350-353, 2015.

Chimura, N., Iio, A., Ozaki, E., Mori, T., Ito, Y., Murayama, N., Nagata, M., Ide, K., Nishifuji, K., Kamishina, H., Maeda, S. Transcription profile of chemokine receptors, cytokines and cytotoxic markers in peripheral blood of dogs with epitheliotropic cutaneous lymphoma. Vet. Dermatol. 2013

Watanabe, S., Koike, A., Kano, R., Nagata, M., Chen, C., Hwang, C.Y., Hasegawa, A., Kamata, H. In vitro susceptibility of Malassezia pachydermatis isolates from canine skin with atopic dermatitis to ketoconazole and itraconazole in East Asia. J. Vet. Med. Sci. 76: 579–581, 2014.

Nagata, M. Mosquito bite. In: Noli, C., Foster, A., Rosenkrantz, W.. eds. Veterinary Allergy. Willy-Blackwell. 2014.
Nagata, M. Canine Papillomaviruses. In: Bonagura, J.D. and Twedt, D.C. eds. Kirk’s Current Veterinary Therapy XV. Elsevier Saunders Co., St. Louis. e184, 2014.

Koike, A., Kano, R., Nagata, M., Chen, C., Hwang, C.Y., Hasegawa, A., Kamata, H. Genotyping of Malassezia pachydermatis isolates from canine healthy 6 skin and lesional skin of atopic dermatitis in Japan, Korea and Taiwan. J. Vet. Med. Sci. 75:955-958, 2013.

Yasuno, K., Kobayashi, R., Mineshige, T., Sugahara, G., Nagata, M., Kamiie, J., Shirota, K. Atypical canine mammary adenoma characterized by cystic ducts comprising a single layer of basaloid cells with myoepithelial differentiation. J. Vet. Med. Sci. 75:1095-1099, 2013.

Nagata, M., Rosenkrantz, W. Cutaneous viral dermatoses in dogs and cats. Compendium: Cont. Ed. Vet. 35: E1-E10, 2013.

Murai, A., Maruyama, S., Nagata, M., Yuki, M. Mastitis caused by Mycobacterium kansasii infection in a dog. Vet. Clin. Pathol. 42:377-381, 2013.

Murayama, N., Nagata, M., Terada, Y., Okuaki, M., Takemura, N., Nakaminami, H., Noguchi, N. In vitro antiseptic susceptibilities for Staphylococcus pseudintermedius isolated from canine superficial pyoderma in Japan. Vet. Dermatol. 24:126-129, 2013.

Terada, Y., Nagata, M., Murayama, N., Nanko, H., Furue, M. Clinical comparison of human and canine atopic dermatitis using human diagnostic criteria (Japanese Dermatological Association, 2009): Proposal of provisional diagnostic criteria for canine atopic dermatitis. J. Dermatol. 38; 784-790, 2011.

Murayama, N., Terada, Y., Okuaki, M., Nagata, M. Dose assessment of 2% chlorhexidine acetate for canine superficial pyoderma. Vet Dermatol. 22; 449-453, 2011.

Chimura, N., Kondo, N., Shibata, S., Kimura, T., Mori, T., Hoshino, Y., Murayama, N., Nagata, M., Ide, K., Nishifuji, K., Kamishina, H., Maeda, S. Gene transcription analysis in lesional skin of canine epitheliotropic cutaneous lymphoma using quantitative real-time RT-PCR. Vet. Immunol immunopathol. 144; 329-336, 2011.

Kobayashi, T., Kano, R., Nagata, M., Hasegawa, A., Kamata, H. Genotyping of Malassezia pachydermatis isolate from canine healthy skin and atopic dermatitis by internal spacer 1 (IGS1) region analysis. Vet Dermatol. 22; 401-405, 2011.
Nijima M, Kano R, Nagata M, Hasegawa A, Kamata H. An azole-resistant isolate of Malassezia pachydermatis.Vet. Microbiol. 149: 288-90, 2011.

Kawakami, T., Shibata, S., Murayama, N., Nagata, M., Nishifuji, K., Iwasaki, T., Fukata, T. Antimicrobial Susceptibility and Methicillin Resistance in Staphylococcus pseudintermedius and Staphylococcus schleiferi subsp. coagulans Isolated from Dogs with Pyoderma in Japan. J. Vet. Med. Sci. 72; 1615-1619, 2010.

Iyori, K., Hisatsune, J., Shibata, S., Murayama, N., Kawakami, T., Ide, K., Nagata, M., Fukata, T., Iwasaki, T., Oshima, K., Hattori, M., Sugai, M., Nishifuji, K. Dentification of a novel Staphylococcus pseudintermedius exfoliative toxin gene and its prevalence among clinical isolates in canine pyoderma. FEMS microbiology letters. 312:169-75, 2010.

Bensignor, E., Nagata, M., Toomet, T. Preliminary multicentric open study for dermocosmetic evaluation of a spot-on formulation composed of polyunsatured fatty acids and essential oil on domestic carnivores. Pratique medical et chirurgicale de l’animal de compagnie. 45; 53-57, 2010.

Murayama, N., Nagata, M., Terada, Y., Shibata, S., Fukata, T. Comparative study of 2% chlorhexidine acetate and 2% chlorhexidine gluconate for canine superficial pyoderma. Vet Record. 167:532-53, 2010.

Murayama, N., Nagata, M., Terada, Y., Shibata, S., Fukata, T. Efficacy of a surgical scrub including 2% chlorhexidine acetate for canine superficial pyodema. Vet Dermatol. 21; 586-592, 2010.

Terada, Y., Murayama, N., Ikemura, H., Morita, T., Nagata, M. Sarcoptes scabiei var. canis refractory to ivermectin treatment in two dogs. Vet Dermatol. 21; 608-612, 2010.

Shimazaki, T., Nagata, M., Goto-Koshino, Y., Tsujimoto, H., Shirota, K. A Case of Canine Lymphomatoid Granulomatosis with Cutaneous Lesions. J. Vet. Med. Sci. 72; 1067-1069, 2010.

Kano, R., Nagata, M., Suzuki, T., Watanabe, S., Kamata, H., Hasegawa, A. Isolation of Trichophyton rubrum var. raubitschekii from a dog. Med. Mycology. 48; 1369-3786, 2010.

Murayama, N., Shibata, K., Nagata, M. Efficacy of oral weekly doramectin in canine demodecosis. Vet Record. 167; 63-64, 2010.

Kawarai, S., Masuda, K., Ohmori, K., Matsuura, S., Yasuda, N., Nagata, M., Sakaguchi, M., Tsujimoto, H. Cultivation and characterzation of canine skin-derived mast cells. J. Vet. Med. Sci. 72; 131-140, 2010.

Baba, T., Shimizu, A., Ohmuro, T., Uchida, N., Shibata, K., Nagata, M., Shirota, K. Auricular chondritis associated with systemic joint and cartilage inflammation in a cat. J. Vet. Med. Sci. 71; 79-82 2009.

Nagata, M. Canine Papillomaviruses. In: Bonagura, J.D. eds. Kirk’s Current Veterinary Therapy XIV. W.B. Saunders Co., Philadelphia. 443-446, 2009.

Murayama, N., Midorikawa, K., Nagata, M. A case of superficial supprative necrolytic dermatitis of miniature schnauzers with identification of causative agent using patch testing. Vet. Dermatol. 19; 395-399, 2008.

Kimura, T., Kano, R., Maeda, S., Tsujimoto, H., Nagata, M., Hasegawa, A. Expression of RANTES mRNA in skin lesions of feline eosinophilic plaque. Vet. Dermatol. 14; 269-273, 2003.

Morita, Y., Kimura, H., Kozawa, K., Nagata, M., Tsuchiya, H., Kato, M., Maruyama, S. Cutaneous infection in a cat caused by Mycobacterium avium complex serovar 6. Vet. Record. 25; 120, 2003.

Kano, R., Hirai, A., Yoshiike, M., Nagata, M., Nakamura, Y., Watanabe, S., Hasegawa, A. Molecular identification of Trichophyton rubrum isolate from a dog by chitin synthase I (CHSI) gene analysis. Med. Mycology. 40; 439-442, 2002.

Tanabe, C., Kano, R., Nagata, M., Nakamura, Y., Watanabe, S., Hasegawa, A. Molecular characteristics of cutaneous papillomavirus from the canine pigmented epidermal nevus. J. Vet. Med. Sci. 62; 1189-1192, 2000.

Nagata, M. Hirata, M. Ishida, T. Hirata, M. Nanko, H. Progressive Langerhans’ cell histocytosis in a puppy. Vet. Dermatol. 11; 241- 246, 2000.

Nagata, M. Canine Papillomaviruses. In: Bonagura, J.D. eds. Kirk’s Current Veterinary Therapy XIII. W.B. Saunders Co., Philadelphia. 569-571, 1999.

Nagata, M., Nanko, H., Hashimoto, K., Ogawa, M., Sakashita, E. Cryoglobulinaemia and cryofibrinogenaemia: a comparison of canine and human cases. Vet. Dermatol. 9; 277-281, 1998.

Konno, M. Nagata, M., Nanko, H. Immunohistochemical diagnosis of a Merkel cell tumor in a dog. Vet. Pathol. 35; 538-540, 1998.

Nagata, M., Ishida, T. Cutaneous reactivity to mosquito bites and its antigens. Vet. Dermatol. 8; 19-26, 1997.
Nagata, M., Iwasaki, T., Masuda, H., Shimizu, H. Non-leathal junctional epidermolysis bullosa in a dog. Br. J. Dermatol. 137; 445-449, 1997.

Iwasaki, T., Shimizu, M., Obata, H., Ogata, M., Nagata, M., Yanai, T., Kitagawa, H., Sasaki, Y. Effect of substrate on indirect immunofluorescence test for canine pemphigus foliaceus. Vet. Pathol. 33; 332-336, 1996.

Nagata, M., Shimizu, H., Masunaga, T., Nishikawa, T., Nanko, H., Kariya, K., Washizu, T., Ishida, T. Dystrophic form of inherited epidermolysis bullosa in a dog (Akita Inu). Br. J. Dermatol. 133; 1000-1003, 1995.

Nagata, M., Nanko, H., Moriyama, A., Washizu, T., Ishida, T. Pigmented plaques associated with papillomavirus infection in dogs. Vet. Dermatol. 6; 179-186, 1995.